The Sunset Blog — Asian Flush, ALDH2 & Alcohol Science

The ALDH2 gene: what it is, how it causes Asian flush, and what to do about it

540 million people worldwide carry a defective copy of the ALDH2 gene — the result of a single amino acid mutation where glutamate swaps to lysin...

Posted in acetaldehyde, alcohol flush reaction, alcohol intolerance, aldh2, aldh2 deficiency, aldh2 gene, aldh2*2, asian flush, enzyme deficiency, genetics

Alcohol intolerance is a metabolic condition in which the body cannot efficiently break down alcohol, leading to adverse physical reactions — fac...

Posted in acetaldehyde, alcohol flush reaction, alcohol intolerance, alcohol sensitivity, ALDH2 deficiency, Asian flush, genetics, histamine intolerance, sudden alcohol intolerance, sulphite sensitivity

Somewhere between 2,000 and 3,000 years ago, in the rice-growing heartlands of central China, a single genetic mutation appeared: ALDH2*2. It spr...

Posted in acetaldehyde, alcohol flush reaction, ALDH2, ALDH2 deficiency, asian flush, Chinese, ethnicity, Filipino, genetics, Japanese, Korean, Vietnamese